Publications

Bhattacharya, Sanchita; Hu, Zicheng; Butte, Atul J;  Opportunities and Challenges in Democratizing Immunology Datasets, Frontiers in immunology, 2021
Tang, Alice S; Oskotsky, Tomiko; Mantyh, William; Solsberg, Caroline Warly; Zeng, Billy; Hu, Zicheng; Oskotsky, Boris; Dubal, Dena; Sirota, Marina;  Deep clinical phenotyping of Alzheimer's Disease Patients Leveraging Electronic Medical Records Data Identifies Sex-Specific Clinical Associations, medRxiv, 2021
Hu, Zicheng; Tang, Alice; Singh, Jaiveer; Bhattacharya, Sanchita; Butte, Atul J;  A robust and interpretable end-to-end deep learning model for cytometry data, Proceedings of the National Academy of Sciences, 2020
Hu, Zicheng; Gruner, Hannah N; Gagacheva, Jana; Gulyaeva, Olga;  KNa1. 1 channels as a target for treating early-onset epilepsy., Nature reviews. Drug discovery, 2020
Lyu, Aram; Triplett, Todd A; Nam, Seo Hee; Hu, Zicheng; Arasappan, Dhivya; Godfrey, Wesley H; Ames, Rachel Y; Sarang, Adviti; Selden, Hilary J; Lee, Chang-Han;  Tumor-associated myeloid cells provide critical support for T-ALL, Blood, 2020
Kaur, Navchetan; Oskotsky, Boris; Butte, Atul J; Hu, Zicheng;  Mining transcriptomics and clinical data reveals ACE2 expression modulators and identifies cardiomyopathy as a risk factor for mortality in COVID-19 patients, medRxiv, 2020
Hu, Zicheng; Glicksberg, Benjamin S; Butte, Atul J;  Robust prediction of clinical outcomes using cytometry data, Bioinformatics, 2019
Lancaster, JN; Thyagarajan, HM; Srinivasan, J; Li, Y; Hu, Z; Ehrlich, LIR;  Live-cell imaging reveals the relative contributions of antigen-presenting cell subsets to thymic central tolerance, Nature communications, 2019
Hu, Zicheng; Gulyaeva, Olga;  TRIC-B: an under-explored druggable ion channel., Nature Reviews Drug Discovery, 2019
Hu, Zicheng; Lancaster, Jessica N; Ehrlich, Lauren IR; Müller, Peter;  Detecting T cell activation using a varying dimension Bayesian model, Journal of applied statistics, 2018
Kan, Matthew J; Zalocusky, Kelly; Hu, Zicheng; Dunn, Patrick; Thomson, Elizabeth; Wiser, Jeffrey; Bhattacharya, Sanchita; Butte, Atul;  The 10,000 immunomes project: a resource for human immunology, Journal of Allergy and Clinical Immunology, 2018
Bhattacharya, Sanchita; Dunn, Patrick; Thomas, Cristel G; Smith, Barry; Schaefer, Henry; Chen, Jieming; Hu, Zicheng; Zalocusky, Kelly A; Shankar, Ravi D; Shen-Orr, Shai S;  ImmPort, toward repurposing of open access immunological assay data for translational and clinical research, Scientific data, 2018
Dekker, Joseph D; Rhee, Catherine; Hu, Zicheng; Lee, Bum-Kyu; Lee, Jiwon; Iyer, Vishwanath R; Ehrlich, Lauren IR; Georgiou, George; Tucker, Haley O; Ippolito, Gregory C;  Lymphoid origin of a lineage of intrinsically activated plasmacytoid dendritic cell in mice and humans, BioRxiv, 2018
Hu, Zicheng; Jujjavarapu, Chethan; Hughey, Jacob J; Andorf, Sandra; Lee, Hao-Chih; Gherardini, Pier Federico; Spitzer, Matthew H; Thomas, Cristel G; Campbell, John; Dunn, Patrick;  MetaCyto: a tool for automated meta-analysis of mass and flow cytometry data, Cell reports, 2018
Zalocusky, Kelly A; Kan, Matthew J; Hu, Zicheng; Dunn, Patrick; Thomson, Elizabeth; Wiser, Jeffrey; Bhattacharya, Sanchita; Butte, Atul J;  The 10,000 immunomes project: building a resource for human immunology, Cell reports, 2018
Aran, Dvir; Hu, Zicheng; Butte, Atul J;  xCell: digitally portraying the tissue cellular heterogeneity landscape, Genome biology, 2017
Hu, Zicheng; Jujjavarapu, Chethan; Hughey, Jake J; Andorf, Sandra; Gherardini, Pier Federico; Spitzer, Matthew H; Dunn, Patrick; Thomas, Cristel G; Campbell, John; Wiser, Jeff;  Meta-analysis of cytometry data reveals racial differences in immune cells, bioRxiv, 2017
Ki, Sanghee; Thyagarajan, Hiran M; Hu, Zicheng; Lancaster, Jessica N; Ehrlich, Lauren IR;  EBI2 contributes to the induction of thymic central tolerance in mice by promoting rapid motility of medullary thymocytes, European journal of immunology, 2017
Zalocusky, Kelly A; Kan, Matthew J; Hu, Zicheng; Dunn, Patrick; Thomson, Elizabeth; Wiser, Jeffrey; Bhattacharya, Sanchita; Butte, Atul J;  The 10,000 Immunomes Project: A resource for human immunology, bioRxiv, 2017
Hu, Zicheng; Li, Yu; Van Nieuwenhuijze, Annemarie; Selden, Hilary J; Jarrett, Angela M; Sorace, Anna G; Yankeelov, Thomas E; Liston, Adrian; Ehrlich, Lauren IR;  CCR7 modulates the generation of thymic regulatory T cells by altering the composition of the thymic dendritic cell compartment, Cell reports, 2017
Triplett, Todd A; Cardenas, Kim T; Lancaster, Jessica N; Hu, Zicheng; Selden, Hilary J; Jasso, Guadalupe J; Balasubramanyam, Sadhana; Chan, Kathy; Li, LiQi; Chen, Xi;  Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation, Proceedings of the National Academy of Sciences, 2016
Hu, Zicheng; Lancaster, Jessica Naomi; Ehrlich, Lauren IR;  The contribution of chemokines and migration to the induction of central tolerance in the thymus, Frontiers in immunology, 2015
Hu, Zicheng; Lancaster, Jessica N; Sasiponganan, Chayanit; Ehrlich, Lauren IR;  CCR4 promotes medullary entry and thymocyte–dendritic cell interactions required for central tolerance, Journal of Experimental Medicine, 2015